Scientist-In-vivo

San Diego, California

Work Arrangement: In Office
2021-10-29

Scientist – In-vivo

One of San Diego’s leading biotech companies is looking for an In-vivo Scientist to add to their dynamic team. This role offers the opportunity to be the technical lead for in-vivo pharmacology studies.

What you will do:

  • Serve as a technical lead for in vivo pharmacology studies to demonstrate efficacy and characterize mechanism of action of lead targets in immunocompetent and immunocompromised mouse models to accomplish the goals of the Translational Sciences team.
  • Work collaboratively with other members of the Translational Sciences team to guide studies for evaluating efficacy and characterizing mechanism of action of lead molecule
  • Serve as the main interface between necessary functions, e.g., Protein Engineering/Biologics, TechOps, etc
  • Train and support personnel to manage and execute complex experimental testing and models.
  • Perform in vivo tumor implant studies with caliper measurement, bioluminescent and fluorescent endpoints, IV/IP/RO test article administration, RO and cardiac puncture blood collection, tissue harvesting for downstream analysis

Who you are:

  • B.S. with minimum 10+ years or M.S. with minimum 8+ years of pharmaceutical industry experience executing in vivo pharmacology studies with immunocompetent and immunocompromised animals in oncology or immunology.
  • Experience with a variety of in vivo translational model systems to demonstrate mechanism of action (immunocompetent and immunocompromised mouse models, GEMM, PDX, etc.)
  • Superior technical expertise with standard in vivo techniques, including dosing and sampling routes (e.g., po, ip, sc, iv dosing; submandibular, retro-orbital, cardiac bleeds; necropsy and organ/tumor harvest) and tumor measurements is required.
  • Competency with mouse surgical techniques (stereotactic implants, orthotopic implants, etc.) will also be highly valued.
  • Experience with managing overall vivarium operations to ensure smooth execution
  • Experience with ex vivo techniques and analysis (tissue extraction, single cell dissociation, multi-color flow cytometry to analyze tumor infiltrates) will be highly valued.
  • Why work here:

    • Stock and equity options: this company wants you to feel a sense of ownership – join their team and you’ll get a little chunk of the business!
    • Collaborative environment: this is a team-centric, culture-oriented company with a focus on leveraging the unique skills of each worker.

    Please email your resume to sshields@provenrecruiting.com if you’d like to work alongside some of the finest professionals in the Biotech industry!

    Note: We actively support and promote people of various backgrounds, from race, religion, gender to geographical area, university, lifestyle, and personality type. Proven Recruiting is minority-owned, majority women, and is a strong advocate for diversity and inclusion in the broader community. Apply today!

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