Senior Protein Production Lead

San Diego, California


Job Description

Title: Protein Purification Associate   

Hours 8-5pm Mon-Fri, flexible hours

Salary range: Depends on Experience


What you’ll do:

  • Develop/perform protein purification processes and characterize enzyme mutants for our DNA sequencing technology.
  • Lead manufacturing activities for continuous supply of enzyme to sustain downstream operation.
  • Develop build plans and inventor and planning methods in collaboration with supervisor
  • Communicate and collaborate with CMO to ensure the quantity and quality of upstream operation.
  • Assist in the development, modification, and implementation of quality control assays and lead activities to use these assays to validate enzyme quality for each lot production.
  • Assist in scaling plan and provide professional estimation on all resources required to support the scaling plan.
  • Coordinate activities with functional groups and project teams.
  • Ability to lead multiple projects simultaneously and efficiently and the ability to collaborate in a multidisciplinary environment.
  • Purify a wide variety of recombinant proteins including antibodies and antibody-based constructs using state-of-the-art techniques in affinity, ion-exchange (IEX), gel-filtration (SEC), reverse-phase chromatograph


Who you are:

  • Requires a B.S./M.S./Ph.D. in Molecular Biology, Biochemistry, Protein Biochemistry, Enzymology or other related discipline.
  • Requires a minimum of 8 years for B.S., 4 years for M.S., 2 years for Ph.D. of hands-on experience in kilogram level protein production.
  • Previous experience operating, maintaining and programming AKTA Avant or Pilot/Unicorn 7.X system, TFF system, high-pressure homogenizer, and equipment for standard downstream protein manufacturing.


Note: We actively support and promote people of various backgrounds, from race, religion, gender to geographical area, university, lifestyle, and personality type. Proven Recruiting is minority-owned, majority women, and is a strong advocate for diversity and inclusion in the broader community. Apply today!



Proven Recruiting